Search results for "Genetics"
Determining actionability of genetic findings in clinical practice
Just as radiology screenings can return results of incidentalomas, genetic scans can also return inadvertent findings. But some guidance can be taken from criteria developed in 1968 for adopting any screening test.
https://immattersacp.org/archives/2012/07/genomics.htm
1 Jul 2012
Recalls for oral docusate sodium, INR monitoring system
This column reviews a recall of an oral liquid docusate sodium solution because of contamination and of an international normalized ratio monitoring system because it may provide significantly lower results than another method.
https://immattersacp.org/archives/2016/09/fda.htm
1 Sep 2016
Why internists should care about lipoprotein(a)
Lipoprotein(a) can be a significant risk factor for heart disease and requires consideration when developing a plan of care, especially in the highest risk patients.
https://immattersacp.org/archives/2020/05/why-internists-should-care-about-lipoproteina.htm
1 May 2020
MKSAP Quiz: 8-year history of joint pain
A 50-year-old man is evaluated for an 8-year history of joint pain, particularly in the hands, and progressively worsening fatigue. Medical history is otherwise unremarkable. He takes ibuprofen as needed. There are swelling and tenderness of the second and third metacarpophalangeal (MCP) joints bilaterally, and tenderness but no swelling of the fourth and fifth MCP joints bilaterally. There is bony hypertrophy of the first MCP joints and knees bilaterally. The proximal interphalangeal joints and wrists are normal. Following a physical exam, lab studies, and a radiograph, what is the most appropriate diagnostic test to perform next?
https://immattersacp.org/archives/2017/05/mksap.htm
1 May 2017
Managing Alzheimer's disease when options are limited
Primary care physicians can expect to diagnose an increasing number of patients with Alzheimer's disease as the U.S. population ages. While clinicians have been more successful in diagnosing the disease early, effective treatments or prevention options are more scarce.
https://immattersacp.org/archives/2016/03/alzheimers.htm
1 Mar 2016
Details debated in breast screening
Amid a thicket of competing and sometimes conflicting studies about breast cancer screening, medical groups have adopted differing stances on how to address the conundrum of harms versus benefits.
https://immattersacp.org/archives/2017/03/breast-screening.htm
1 Mar 2017
Study examines patients' perspectives on direct-to-consumer genetic tests
An editorial concluded that deceptive marketing messages by genomic testing companies create unrealistic expectations about the health benefits of at-home genetic tests.
https://immattersacp.org/weekly/archives/2016/03/01/1.htm
1 Mar 2016
New options no panacea for depression
Internists can have the greatest impact by continuing to be the first point of contact, treating mild to moderate depression, and explaining what may be available if first-line options fall short.
https://immattersacp.org/archives/2019/09/new-options-no-panacea-for-depression.htm
1 Sep 2019
Taking the leap forward to precision medicine
Genomic targeted therapies may finally deliver the full promise of knowing the family medical history or considering environmental factors during a clinical examination.
https://immattersacp.org/archives/2015/09/precision-medicine.htm
1 Sep 2015
Catheters, infusion pumps recalled
This column reviews details on recent recalls, warnings, and approvals.
https://immattersacp.org/archives/2021/02/catheters-infusion-pumps-recalled.htm
1 Feb 2021