Search results for "Statins"
The never-ending push-pull of statins
Statins have proven their potential to reduce end-point outcomes, such as death from cardiovascular disease. But the drug class also has some downsides, and the pros and the cons become a close call.
https://immattersacp.org/archives/2017/04/statins.htm
1 Apr 2017
More than half of people taking statins may have suboptimal improvement in LDL cholesterol
There was a significantly increased risk of coronary artery disease, peripheral vascular disease, and cardiovascular disease-related death in patients with a suboptimal response to statins compared with those with an optimal response.
https://immattersacp.org/weekly/archives/2019/04/23/1.htm
23 Apr 2019
Examination of statin use in relation to guidelines reveals underuse in CKD patients
Differing statin guidelines are fairly concordant on use of the drugs in adults with chronic kidney disease (CKD), a study found.
https://immattersacp.org/weekly/archives/2014/11/25/5.htm
25 Nov 2014
High-intensity statins often not prescribed after CHD hospitalization, study finds
Patients who are hospitalized for coronary heart disease (CHD) often don't fill prescriptions for high-intensity statins after discharge, according to a new study.
https://immattersacp.org/weekly/archives/2015/01/27/2.htm
27 Jan 2015
Clarithromycin may cause serious adverse events when taken with certain statins
Clarithromycin may cause serious adverse events when taken with rosuvastatin, pravastatin, or fluvastatin, according to a new study.
https://immattersacp.org/weekly/archives/2015/01/13/6.htm
13 Jan 2015
Oldest patients least likely to receive statins despite potential benefits, study finds
Patients older than age 75 years were less likely to receive moderate- or high-intensity statins than those ages 65 to 75 years despite their higher incidence of atherosclerotic cardiovascular disease.
https://immattersacp.org/weekly/archives/2021/09/21/4.htm
21 Sep 2021
Measure of coronary artery calcium might spare statins in some elderly patients
Coronary artery calcium-guided reclassification improved specificity for coronary heart disease events by 22% without any significant loss in sensitivity, while reclassification based on carotid plaque burden improved specificity 16% with a 7% loss in sensitivity, a study found.
https://immattersacp.org/weekly/archives/2016/08/23/1.htm
23 Aug 2016
Statins may be significantly overprescribed for primary prevention, computer model suggests
An analysis compared risk of drug-related events, including myopathy, hepatic dysfunction, and incident diabetes, to predicted cardiovascular benefit for men and women at various ages.
https://immattersacp.org/weekly/archives/2018/12/04/1.htm
4 Dec 2018
USPSTF issues recommendations on statins for primary prevention
Among other recommendations, low- to moderate-dose statins should be started in adults 40 to 75 years of age who have no history of cardiovascular disease (CVD) but have at least 1 risk factor and a 10-year CVD event risk calculated at 10% or more.
https://immattersacp.org/weekly/archives/2016/11/15/1.htm
15 Nov 2016
Use caution with colchicine's many drug interactions
A coauthor of “The Top 100 Drug Interactions” offers advice for improved management of colchicine.
https://immattersacp.org/archives/2023/09/use-caution-with-colchicines-many-drug-interactions.htm
1 Sep 2023