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MKSAP Quiz: 7-year history of plaques

A 50-year-old man is evaluated in the hospital for fatigue, joint pain, and skin lesions. His symptoms started 2 weeks ago with fever and sore throat, which subsided in 2 days. Fatigue and joint pain were noted 1 day after the onset of sore throat, which worsened over the subsequent days. Four days after the onset of symptoms, he noted dark red spots on his ankles and shins, which spread to involve his legs, thighs, and buttocks; the skin lesions were not painful or itchy. Following a physical exam and lab studies, what is the most likely diagnosis?
https://immattersacp.org/archives/2018/03/mksap-quiz-7-year-history-of-plaques.htm
1 Mar 2018

MKSAP Quiz: 5-year history of recurrent gout

A 53-year-old man is evaluated for a 5-year history of recurrent gout attacks involving the base of the great toes, mid feet, and ankles. Episodes are becoming more frequent and severe. History is also significant for hypertension and stage 3 chronic kidney disease. Following a physical exam and lab studies, what is the most appropriate next step in management?
https://immattersacp.org/weekly/archives/2018/12/11/3.htm
11 Dec 2018

MKSAP Quiz: 6-week history of blisters

A 55-year-old man is evaluated for a 6-week history of blisters on his hands. The blisters are tender, break easily after they develop, and occur in different regions on the backs of his hands. Medical history is notable for alcoholic liver disease. The patient does not use tobacco but drinks 6 beers daily. He takes no medications. Following a physical exam, what is the most likely diagnosis?
https://immattersacp.org/archives/2017/09/mksap-quiz-6-week-history-of-blisters.htm
1 Sep 2017

MKSAP Quiz: Frequently fluctuating INRs

A 77-year-old woman is evaluated for frequently fluctuating INRs (<1.8 to >3.5) while taking warfarin therapy. She has undergone INR testing every 1 to 2 weeks and frequent warfarin dose adjustments. She reports a consistent dietary intake. Following a physical exam, what is the most appropriate next step in management?
https://immattersacp.org/weekly/archives/2018/05/01/3.htm
1 May 2018

DynaMed Plus Quiz: Shortness of breath

A 40-year-old trophy-winning professional knitter reports increasing shortness of breath and dry cough for the past week, as well as hoarseness and throat pain for the past three days. Upon questioning, she reports feeling “feverish” and being unusually tired of late. Following a review of systems, physical exam, and lab tests, what is the most likely diagnosis?
https://immattersacp.org/archives/2017/11/dynamed-plus-quiz-shortness-of-breath.htm
1 Nov 2017

MKSAP Quiz: fatigue, anorexia, polyuria, and nocturia

A 54-year-old woman is evaluated for fatigue, anorexia, polyuria, and nocturia of several weeks' duration. She had otherwise felt well until the onset of her current symptoms. Medical history is significant for autoimmune pancreatitis diagnosed 1 year ago, treated with a prednisone taper that was completed 8 months ago with resolution of her symptoms. Following a physical exam and lab studies, what is the most likely diagnosis?
https://immattersacp.org/weekly/archives/2016/06/14/3.htm
14 Jun 2016

MKSAP Quiz: Red, scaly skin lesions

A 37-year-old man is evaluated for a 4-month history of progressively worsening red, scaly lesions involving the scalp, trunk, and extremities. During the past month, he also has had pain in the hands and feet and has lost 4.5 kg (10.0 lb). Aspirin and acetaminophen have helped to relieve his joint symptoms. He does not drink alcoholic beverages, has no other medical problems, and takes no additional medications. He denies allergies. He has sex with men and women and uses condoms inconsistently. What diagnostic studies should be performed next in this patient?.
https://immattersacp.org/archives/2011/03/mksap.htm
1 Mar 2011

MKSAP Quiz: evaluation of painful nodules and rash

A 21-year-old woman is evaluated for a 3-week history of painful nodules and a rash in the lower extremities, along with pain and swelling of the wrists, knees, and ankles. She reports a low-grade fever and a 2.7-kg (6.0-lb) weight loss since the onset of symptoms. She has taken naproxen with some relief. History is significant for gastroesophageal reflux disease and acne. Medications are over-the-counter famotidine as needed and minocycline. Following a physical exam and lab studies, what is the most appropriate next step in management?
https://immattersacp.org/weekly/archives/2015/11/03/3.htm
3 Nov 2015

It's all about the history in diagnosing fever of unknown origin

There are 4 types of fever of unknown origin, and distinguishing among them starts with the first step: Look for clues from the history and other presenting symptoms.
https://immattersacp.org/archives/2014/06/fever.htm
1 Jun 2014

MKSAP Quiz: Rash, pain, fever and fatigue

A 48-year-old woman is evaluated for a rash on her legs, arthralgia and myalgia, low-grade fever, and fatigue of 4 weeks' duration.
https://immattersacp.org/archives/2011/06/MKSAP.htm
1 Jun 2011

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