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MKSAP Quiz: 1-month history of malaise, myalgia, weight loss

A 65-year-old man is evaluated for a 1-month history of progressive malaise, myalgia, a 3.6-kg (8.0-lb) weight loss, and numbness and weakness of the right foot; left testicular pain for 1 week; and a painful rash on his legs for 2 days. Following a physical exam, lab studies, and other tests, what is the most likely diagnosis?
https://immattersacp.org/weekly/archives/2019/03/12/3.htm
12 Mar 2019

Leflunomide gets boxed warning, ARBs under review

Recalls, warnings, approvals and other regulatory news.
https://immattersacp.org/archives/2010/09/fda.htm
1 Sep 2010

MKSAP quiz: 2-week history of rash on face, midchest

This week's quiz asks readers to determine the most likely diagnosis for a 32-year-old man evaluated for a 2-week history of a rash on his face and midchest consisting of small, reddish, intensely itchy “lumps.”
https://immattersacp.org/weekly/archives/2017/08/29/4.htm
29 Aug 2017

Actavis recalls more than 60 generics, six flu vaccines OK'd

The latest recalls, warnings, label changes and approvals from the Food and Drug Administration.
https://immattersacp.org/archives/2008/10/fda.htm
1 Oct 2008

MKSAP Quiz: 2-month history of edema

A 28-year-old man is evaluated for a 2-month history of progressive lower-extremity edema, weight loss, and fatigue. Medical history is significant for recreational use of inhaled cocaine; he denies injection drug use. He has no other known medical issues and takes no medications. Following a physical exam, lab studies, and kidney analysis, what test is most likely to establish the cause of this patient's focal segmental glomerulosclerosis?
https://immattersacp.org/weekly/archives/2018/02/06/3.htm
6 Feb 2018

MKSAP Quiz: 2-month history of headaches, nausea, visual disturbance, difficulty speaking

A 79-year-old man is evaluated for a 2-month history of progressively worsening headaches, nausea, visual disturbance, and difficulty speaking. Following a physical exam and MRI of the brain, what is the most appropriate next step in management?
https://immattersacp.org/weekly/archives/2018/10/16/3.htm
16 Oct 2018

MKSAP Quiz: 4 days of fever and arthralgia

A 43-year-old man is evaluated for 4 days of fever and arthralgia, as well as a raised purple rash over his lower extremities of 1 week's duration. He is a current intravenous drug user. He has no other medical problems and takes no medications. Following a physical exam, lab studies, and skin findings, what is the most appropriate treatment?
https://immattersacp.org/archives/2019/05/mksap-quiz-4-days-of-fever-and-arthralgia.htm
1 May 2019

U.S. Preventive Services Task Force recommends PrEP for HIV in high-risk patients

The Grade A recommendation was based on a systematic review of the literature that looked at the benefits of PrEP with oral tenofovir disoproxil fumarate monotherapy or combined tenofovir disoproxil and emtricitabine.
https://immattersacp.org/weekly/archives/2019/06/18/1.htm
18 Jun 2019

Insulin cartridge holders recalled, HCV drug approved

This column reviews details on recent recalls, warnings, and approvals.
https://immattersacp.org/archives/2017/09/insulin-cartridge-holders-recalled-hcv-drug-approved.htm
1 Sep 2017

MKSAP Quiz: 2-week history of a rash on face and midchest

A 32-year-old man is evaluated for a 2-week history of a rash on his face and midchest. He describes the rash as consisting of small, reddish “lumps” that are intensely itchy; they develop and begin to resolve with development of new lesions. He otherwise feels well. Medical history is significant for a recent diagnosis of HIV infection. Following a physical exam and lab studies, what is the most likely diagnosis?
https://immattersacp.org/weekly/archives/2016/04/12/3.htm
12 Apr 2016

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