Search results for "Fracture risk"
Atypical femur fracture risk increases with longer bisphosphonate use, drops after discontinuation
Researchers studied women ages 50 years or older who took bisphosphonates and were enrolled in the Kaiser Permanente Southern California health care system.
https://immattersacp.org/weekly/archives/2020/08/25/3.htm
25 Aug 2020
DOACs associated with lower risk of fracture than warfarin in atrial fibrillation
Patients taking apixaban, dabigatran, or rivaroxaban had lower rates of hip and vertebral fractures than those taking warfarin, with no difference seen between the direct oral anticoagulants (DOACs).
https://immattersacp.org/weekly/archives/2020/05/19/2.htm
19 May 2020
Physical activity in women may reduce risk for some fractures over time
An analysis of data from the Women's Health Initiative found that total physical activity in postmenopausal women was inversely associated with risk of total and hip fracture but positively associated with risk of knee fracture over 14 years of follow-up.
https://immattersacp.org/weekly/archives/2019/10/29/2.htm
29 Oct 2019
Bisphosphonates associated with lower fracture risk, not associated with mortality
Lower mortality rates linked to bisphosphonates in previous observational studies might be due to direct biological effects of treatment, authors of a recent meta-analysis noted.
https://immattersacp.org/weekly/archives/2019/08/27/4.htm
27 Aug 2019
Osteoporosis associated with significant five-year risk of hip fracture in women 80 years and older
Women with osteoporosis had similar mortality risk, but much higher rates of hip fracture, compared to those without osteoporosis but with other risk factors for fracture.
https://immattersacp.org/weekly/archives/2019/06/25/4.htm
25 Jun 2019
Guideline recommends pharmacologic treatment of osteoporosis in postmenopausal women at high fracture risk
Bisphosphonates are recommended for initial treatment, although ibandronate is not recommended for reducing nonvertebral or hip fracture risk, the clinical practice guideline from the Endocrine Society stated.
https://immattersacp.org/weekly/archives/2019/04/02/4.htm
2 Apr 2019
Canagliflozin may not increase fracture risk in patients at low risk for fractures
Although canagliflozin has been linked to decreased bone mineral density, patients with type 2 diabetes who initiated the drug had similar risk of a first fracture as those who started a glucagon-like peptide-1 receptor agonist.
https://immattersacp.org/weekly/archives/2019/01/08/2.htm
8 Jan 2019
Association between antidepressants and hip fracture in elderly patients may not be causal
Antidepressant users had more than twice as many hip fractures as nonusers, but this was true both in the year before and the year after starting antidepressant therapy, and the association was strongest immediately before antidepressant initiation.
https://immattersacp.org/weekly/archives/2019/01/08/1.htm
8 Jan 2019
A defense of proton-pump inhibitors
Data on their risks may seem persuasive, but one expert is not convinced.
https://immattersacp.org/archives/2019/01/a-defense-of-proton-pump-inhibitors.htm
1 Jan 2019
Osteoporosis treatment often not started after hip fracture in elderly patients, study finds
The study found a continuous decline in starting osteoporosis treatment after hip fracture from 2004 to 2015, as well as a clinically meaningful reduction in rate of subsequent nonvertebral fracture in patients who did begin treatment versus those who did not.
https://immattersacp.org/weekly/archives/2018/07/24/4.htm
24 Jul 2018