Welcome to this month's issue of ACP DiabetesMonthly, an update for internists published by the American College of Physicians.
In the News for the month of October 2014
Hypertension treatment reduced long-term mortality, but intensive glucose control didn't
Hypertension treatment with perindopril-indapamide for 4.5 years had a long-lasting impact on mortality in patients with type 2 diabetes, but intensive glucose control was not associated with any significant benefit, a study found. More...
Metformin may be associated with low levels of thyroid-stimulating hormone, study finds
Metformin monotherapy may be linked to lower levels of thyroid-stimulating hormone compared with sulfonylurea monotherapy in patients with type 2 diabetes, according to a new study. More...
Phentermine/topiramate combo helps type 2 diabetes patients lose weight, control glucose
Obese and overweight patients with type 2 diabetes lost more weight and had better glycemic control when treated with phentermine/topiramate extended-release medication than with placebo, 2 industry-funded studies reported. More...
MKSAP quiz: Severe foot pain in type 1 diabetic
This month's quiz asks readers to evaluate a 42-year-old man with poorly controlled type 1 diabetes who has a 6-day history of severe burning and stabbing pain in both feet that is worse in the toes. More...
From ACP Journal Club
In newly diagnosed type 2 diabetes mellitus, a Mediterranean diet (vs. a low-fat diet) delayed start of glucose-lowering drugs
Patients who were randomized to a low-carbohydrate Mediterranean diet shortly after type 2 diabetes diagnosis delayed their need for medication compared to those put on a low-fat diet in an Italian trial. More...
From ACP Internist Weekly
GLP-1 agonist plus basal insulin beat other diabetes treatment regimens in meta-analysis
Patients on combination treatment with a glucagon-like peptide-1 receptor (GLP-1) agonist and basal insulin had better HbA1c values, less weight gain, and similar hypoglycemia rates compared to patients on other type 2 diabetes treatment regimens, a recent analysis of previous trials found. More...
USPSTF recommends screening asymptomatic adults for diabetes
The United States Preventive Services Task Force (USPSTF) is expanding the population it recommends screening for type 2 diabetes, according to a draft recommendation released this week. More...
New GLP-1 agonist approved
A new glucagon-like peptide-1 (GLP-1) receptor agonist, dulaglutide (Trulicity), was approved to treat type 2 diabetes, along with diet and exercise, the FDA recently announced. More...
Spotlight on ethnic differences in diabetes
Two recent studies highlighted some differences among ethnic groups in risk and incidence of diabetes. More...
Physician editor: David V. O'Dell, MD, FACP
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A 72-year-old woman is evaluated during a routine examination. She has very severe COPD with multiple exacerbations. She has dyspnea at all times with decreased exercise capacity. She does not have cough or any change in baseline sputum production. She is adherent to her medication regimen, and she completed pulmonary rehabilitation 1 year ago. She quit smoking 1 year ago. Her medications are a budesonide/formoterol inhaler, tiotropium, and an albuterol inhaler as needed. Following a physical and pulmonary exam, what is the most appropriate next step in management?
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