A 35-year-old man is evaluated during a routine visit for β-thalassemia intermedia. One year ago, he began requiring erythrocyte transfusions every 4 to 6 months for symptomatic anemia. He has no other symptoms or medical problems, and his only medication is folic acid. Following a physical exam and lab studies, what is the most appropriate additional management?
12 Sep 2023
Primary care physicians play a crucial role in ongoing anticoagulation management, including educating patients about the signs of venous thromboembolism.
1 Apr 2022
Three variables were associated with receiving anticoagulation for longer than three months after a provoked venous thromboembolism (VTE): direct oral anticoagulant use, history of VTE, and history of myocardial infarction.
1 Nov 2022
A recent book addresses perioperative medicine, including how to be a perioperative consultant, prophylaxis for venous thromboembolism, coexisting medical problems, and common postoperative complications.
1 Feb 2022
For patients with venous thromboembolism, initiation of apixaban was associated with lower rates of recurrence and intracranial and gastrointestinal bleeding than rivaroxaban in a population-based cohort study.
7 Dec 2021
Patients with first-time venous thromboembolism (VTE) who weighed 120 kg or more and had a body mass index (BMI) of 40 kg/m2 or more were not at higher risk for bleeding or recurrent VTE with direct-acting oral anticoagulants (DOACs) versus warfarin.
9 Nov 2021
Experts debate about provoked vs. unprovoked venous thromboembolism, and whether a once-high-risk patient can have that status removed later.
1 Feb 2020
A 56-year-old woman is evaluated for a 2-year history of worsening hot flashes and night sweats. She reports that the night sweats awaken her several times nightly, resulting in fatigue and missed work. Following a physical exam, what is the most appropriate treatment?
20 Dec 2022
A 37-year-old transgender woman (genetic male, identifies as a female) requests feminizing hormone therapy. She was diagnosed with gender dysphoria by her psychiatrist in accordance with DSM-5 criteria. Following lab studies, what treatment risks should be reviewed with the patient?
6 Jun 2023
A 59-year-old woman is evaluated in the emergency department for midsternal chest pain. The pain began several hours ago as a vague ache in her left upper sternal region that progressed in intensity and severity. The pain abated spontaneously after approximately 45 minutes. She had no further chest pain until several hours later, when it recurred unprovoked by exertion. She has no shortness of breath, nausea or vomiting, syncope, previous history of chest pain, or known cardiac disease or risk factors for venous thromboembolism. Medical history is significant for hyperlipidemia and hypertension. She does not smoke cigarettes. Medications are simvastatin, aspirin, lisinopril, and hydrochlorothiazide. Following a physical exam, electrocardiogram and chest radiograph, what is the most appropriate initial management?.
1 Apr 2014