A 72-year-old man is hospitalized for dyspnea, night sweats, and productive cough; symptoms began 8 months ago. He also reports a 9.1-kg (20 lb) weight loss over the past 12 months. Medical history is notable for COPD. Following a physical exam, lab tests, and a chest radiograph, what is the most likely causative organism?
1 Jan 2023
Expanded recommendations specifically include use in children, in persons co-infected with HIV/AIDS and latent tuberculosis, and by self-administration.
10 Jul 2018
Among the recommendations are tuberculosis screening with an individual risk assessment and symptom evaluation at baseline (preplacement) and tuberculosis testing with an interferon-gamma release assay or a tuberculin skin test for people without documented prior latent tuberculosis.
21 May 2019
A 43-year-old man is evaluated for difficulty with swallowing and painful swallowing. The pain began approximately 5 days ago and occurs with both solids and liquids. He has recently diagnosed HIV infection and is receiving antiretroviral therapy. Following a physical exam and lab studies, what is the most appropriate treatment?
1 Sep 2022
A 4-drug regimen of isoniazid, rifampin, pyrazinamide, and ethambutol, followed by a continuation phase of 4 months of isoniazid and rifampin, remains the preferred initial treatment.
16 Aug 2016
A 28-year-old man is evaluated after being informed his roommate at a homeless shelter was diagnosed with pulmonary tuberculosis. He reports no fever, cough, night sweats, or weight loss. Medical history is significant for injection drug use, most recently 2 weeks ago, although he reports no known infectious complications in the past. Following physical exams and other tests, what is the most appropriate next step in the management of this patient?
7 Jun 2016
Patients with undiagnosed chronic obstructive pulmonary disease (COPD) can sometimes hide in plain sight.
1 Sep 2022
Self-administered therapy with monthly monitoring could be an acceptable strategy for treating latent tuberculosis in the U.S., as well as in other countries and settings when directly observed therapy is not possible.
7 Nov 2017
A 24-year-old woman is evaluated for a 6-week history of weight loss, fever, night sweats, and productive cough, with recently increasing malaise and fatigue. She works in a state prison. She takes no medications. Following a physical exam and other tests, what is the most appropriate initial treatment?
1 Jan 2022
Early-stage studies attempting to shorten tuberculosis treatment regimens in African countries from 6 months to 4 months by including a fluoroquinolone failed to show noninferiority, according to 3 published reports and an editorial that appeared in the New England Journal of Medicine on Oct. 23.
28 Oct 2014