A 35-year-old man is evaluated during a routine visit for β-thalassemia intermedia. One year ago, he began requiring erythrocyte transfusions every 4 to 6 months for symptomatic anemia. He has no other symptoms or medical problems, and his only medication is folic acid. Following a physical exam and lab studies, what is the most appropriate additional management?
12 Sep 2023
Internal medicine physicians play a critical role in educating patients about the seriousness of transient ischemic attacks and preventing their recurrence.
1 May 2023
Amiodarone increases bleeding compared with flecainide or sotalol in patients on anticoagulant therapy
A retrospective analysis of Medicare patients who started an anticoagulant and then amiodarone found that they had a 44% increased risk for bleeding-related hospitalization compared to those on other antiarrhythmics and that this risk was higher with rivaroxaban than apixaban.
23 May 2023
Three variables were associated with receiving anticoagulation for longer than three months after a provoked venous thromboembolism (VTE): direct oral anticoagulant use, history of VTE, and history of myocardial infarction.
1 Nov 2022
A 24-year-old woman is evaluated for pain in the right calf since yesterday. She reports no shortness of breath, cough, or chest pain. Her medical history is unremarkable. Following a physical exam and ultrasound, what is the most appropriate management?
4 Jul 2023
Women were significantly less likely than men to underestimate their bleeding risk, and a history of bleeding was associated with a threefold increased likelihood of inaccurate perception of bleeding risk, according to a study of atrial fibrillation patients.
24 Aug 2021
Results from a systematic review and meta-analysis provide a framework for clinicians and patients to balance the benefits and harms of extended anticoagulation for unprovoked venous thromboembolism (VTE).
14 Sep 2021
Electronic messaging and academic detailing improved clinicians' comfort with prescribing anticoagulation in certain situations, but rates of appropriate anticoagulation for atrial fibrillation did not change significantly, a trial found.
25 Feb 2020
Researchers published evidence of re-infection with SARS-CoV-2, anticoagulation was associated with halved inpatient mortality, recommendations were made on pulmonary embolism in COVID-19, and a study attributed differences in men's and women's outcomes to T cells.
1 Sep 2020
Two new studies support prophylactic, rather than therapeutic, anticoagulation for COVID-19 patients, and case reports provide more information about vaccine-induced immune thrombotic thrombocytopenia.
15 Jun 2021