Search results for "Osteoarthritis"
MKSAP Quiz: 8-year history of joint pain
A 50-year-old man is evaluated for an 8-year history of joint pain, particularly in the hands, and progressively worsening fatigue. Medical history is otherwise unremarkable. He takes ibuprofen as needed. There are swelling and tenderness of the second and third metacarpophalangeal (MCP) joints bilaterally, and tenderness but no swelling of the fourth and fifth MCP joints bilaterally. There is bony hypertrophy of the first MCP joints and knees bilaterally. The proximal interphalangeal joints and wrists are normal. Following a physical exam, lab studies, and a radiograph, what is the most appropriate diagnostic test to perform next?
https://immattersacp.org/archives/2017/05/mksap.htm
1 May 2017
Intra-articular steroid injections not warranted for knee osteoarthritis, study suggests
Cartilage volume loss was significantly greater in the triamcinolone group than in the placebo group, and there was no significant difference in pain between groups.
https://immattersacp.org/weekly/archives/2017/05/23/4.htm
23 May 2017
New drug treats cancer based on biomarker, not location
This column reviews details on recent recalls, warnings, and approvals.
https://immattersacp.org/archives/2017/07/new-drug-treats-cancer-based-on-biomarker-not-location.htm
1 Jul 2017
DynaMed Plus Quiz: Shortness of breath
A 40-year-old trophy-winning professional knitter reports increasing shortness of breath and dry cough for the past week, as well as hoarseness and throat pain for the past three days. Upon questioning, she reports feeling “feverish” and being unusually tired of late. Following a review of systems, physical exam, and lab tests, what is the most likely diagnosis?
https://immattersacp.org/archives/2017/11/dynamed-plus-quiz-shortness-of-breath.htm
1 Nov 2017
Gout drug concerns; monthly buprenorphine injection OK'd
This column reviews details on recent recalls, warnings, and approvals.
https://immattersacp.org/archives/2018/02/gout-drug-concerns-monthly-buprenorphine-injection-okd.htm
1 Feb 2018
Off-label hydroxychloroquine no more effective than placebo when added to usual care for osteoarthritis hand pain
Findings do not support the current practice of off-label use of hydroxychloroquine in patients with hand osteoarthritis, but that should not deter research and drug development communities from researching more potent agents or compounds that more specifically target the inflammatory pathways, editorialists said.
https://immattersacp.org/weekly/archives/2018/02/27/2.htm
27 Feb 2018
Opioids not superior to nonopioid analgesics for back pain, hip or knee osteoarthritis
There was no significant difference between groups in pain-related function, and while pain intensity was significantly better in the nonopioid group, the result did not reach a clinically predetermined level of importance.
https://immattersacp.org/weekly/archives/2018/03/13/4.htm
13 Mar 2018
First blood test approved to evaluate concussion
This column reviews details on recent recalls, warnings, and approvals.
https://immattersacp.org/archives/2018/04/first-blood-test-approved-to-evaluate-concussion.htm
1 Apr 2018
Nondrug treatments assessed for chronic pain relief
Most effects were small and long-term evidence was sparse, and while there was no evidence suggesting serious harms from any of the interventions studied, data on harms were limited.
https://immattersacp.org/weekly/archives/2018/06/19/4.htm
19 Jun 2018
Long-term weight loss of at least 20% helps improve outcomes in overweight, obese patients with knee osteoarthritis
Overweight and obese adults with pain and radiographically confirmed knee osteoarthritis who had participated in the Intensive Diet and Exercise for Arthritis study were characterized according to their weight loss over 18 months: less than 5%, at least 5%, at least 10%, and at least 20%.
https://immattersacp.org/weekly/archives/2018/06/26/4.htm
26 Jun 2018