A 35-year-old woman is evaluated for worsening thrombocytopenia; she is pregnant at 36 weeks' gestation. Medical history is significant for immune thrombocytopenic purpura. Previous platelet counts during this pregnancy have been 80,000 to 100,000/##mu;L (80-100 x 109/L). Her only medication is a prenatal vitamin. Following a physical exam and lab results, what is the most appropriate management of this patient's thrombocytopenia?.
1 Sep 2016
Physicians who care for adult patients with congenital heart disease should be mindful of the effects that the condition has on other organs, according to a scientific statement from the American Heart Association.
17 Oct 2017
Fewer splenectomies are being done, but thromboembolic disease afterward is now more recognized and therefore being diagnosed more frequently.
1 Apr 2017
There are now more medical school applicants than ever, and internal medicine underwent its largest Match in history. Experts weigh in on what's driving the sudden surge.
1 Jul 2021
A 68-year-old woman is hospitalized with fatigue, anorexia, and myalgia worsening over the last week. She underwent laparotomy 4 weeks ago for trauma sustained in a motor vehicle accident, which necessitated a splenectomy. She received 3 units of blood. Which of the following transfusion-transmitted diseases is the most likely diagnosis?
1 May 2020
New evidence-based guidelines on the management of sickle cell disease were released last week by a group of experts convened by the National Heart, Lung, and Blood Institute.
16 Sep 2014
A 77-year-old woman is evaluated for frequently fluctuating INRs (<1.8 to >3.5) while taking warfarin therapy. She has undergone INR testing every 1 to 2 weeks and frequent warfarin dose adjustments. She reports a consistent dietary intake. Following a physical exam, what is the most appropriate next step in management?
1 May 2018
A 32-year-old woman is evaluated for anticoagulation management after an uncomplicated vaginal delivery of a healthy newborn. She was diagnosed with a bilateral pulmonary embolism at 25 weeks' gestation and was treated with therapeutic low-molecular-weight heparin (LMWH). The LMWH was discontinued at the onset of labor and was restarted 6 hours after delivery. Medical history is otherwise unremarkable, and her only medication is full-dose LMWH. Anticoagulation for 3 months is planned. The patient wishes to breastfeed her newborn. What is the most appropriate anticoagulation option for this patient?
23 Feb 2016
An 81-year-old man is evaluated for increasing fatigue. He has no other symptoms to report. Medical history is significant for diabetes mellitus and hypertension. He does not drink alcohol or smoke. Following a physical exam and lab studies, what is the most appropriate diagnostic test to perform next to evaluate this patient's anemia?
1 Sep 2019
The Governance Committee of the American College of Physicians places in nomination candidates for College governance.
1 Nov 2019