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New warnings for opioids; approval for arthritis drug

This column reviews a warning on opioid pain drugs and cough medicines combined with benzodiazepines and approval of a new drug to treat multiple inflammatory diseases.
https://immattersacp.org/archives/2016/11/fda.htm
1 Nov 2016

Updated warnings on fluoroquinolones, new diabetes drug

This column reviews a warning on fluoroquinolones with a risk of disabling and potentially permanent side effects, as well as approval of an injection to improve glycemic control in adults with type 2 diabetes.
https://immattersacp.org/archives/2016/10/fda.htm
1 Oct 2016

Keys to taking a neurological history

The most powerful tool in neurology is the history and physical exam, including the requirement that patients walk in the presence of neurologists, in order to better understand symptoms.
https://immattersacp.org/archives/2016/07/neurology.htm
1 Jul 2016

MKSAP Quiz: severe, persistent, burning pain in an assisted-living patient

An 86-year-old woman is evaluated in her assisted-living facility for pain. Four weeks ago, she developed herpetic lesions on her right posterior thorax in a T7 distribution. She was treated with acyclovir, and the lesions healed; however, she has persistent severe burning pain. The pain is so severe that she is unable to leave her bed to attend meals. Following a physical exam, which medication is the most appropriate pharmacologic therapy for this patient's pain?
https://immattersacp.org/weekly/archives/2016/05/17/3.htm
17 May 2016

Managing depression is worth the effort

Depression's impact on health is often profound and far-reaching, potentially equaling that of coronary artery disease. To provide clinicians with guidance on treatment of depression, ACP has released a new clinical practice guideline that underscores the severe burden of depression and outlines viable treatment options for patients.
https://immattersacp.org/archives/2016/05/depression.htm
1 May 2016

Statin treatment reduced cardiovascular events more than hypertension drugs in intermediate-risk patients, study finds

An accompanying editorial said that the results of this trial support the benefits of statins for primary prevention and a risk-based approach to prescribing, rather than one based on LDL levels.
https://immattersacp.org/weekly/archives/2016/04/05/1.htm
5 Apr 2016

Corticosteroids may be viable first-line alternative to NSAIDs for acute gout

The study provides evidence that oral corticosteroids are as effective at treating pain and as acceptable to patients as non-steroidal anti-inflammatory drugs, and that they should be considered as a first-line alternative in the treatment of patients with acute gout.
https://immattersacp.org/weekly/archives/2016/02/23/4.htm
23 Feb 2016

New warnings added on multiple diabetes drugs

This update also covers a risk evaluation and mitigation strategy for liraglutide and approval of a new PCSK9 inhibitor.
https://immattersacp.org/archives/2015/11/fda.htm
1 Nov 2015

Warning on medication confusion, recalls due to sterility

This update covers possible confusion between an antidepressant and an anti-clotting drug, as well as 2 sterility warnings.
https://immattersacp.org/archives/2015/10/fda.htm
1 Oct 2015

MKSAP Quiz: 3-week history of progressive fatigue

A 28-year-old previously healthy woman is evaluated in the hospital for a 3-week history of progressive fatigue, dyspnea with exertion, and easy bruisability. What is the most likely diagnosis?.
https://immattersacp.org/archives/2015/06/mksap.htm
1 Jun 2015

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