Meta-regression analysis showed that the difference between angiotensin-converting enzyme (ACE) inhibitors and angiotensin-receptor blockers (ARBs) compared with placebo was due to a higher placebo event rate in the ACE inhibitor trials for the outcome of all-cause mortality, cardiovascular death, and myocardial infarction.
12 Jan 2016
Dual antiplatelet therapy may be safer than triple therapy in older patients with acute MI, afib after PCI
Older patients with acute myocardial infarction and atrial fibrillation who have undergone percutaneous coronary intervention appear to have a higher risk for major bleeding, both early and long-term, with triple therapy versus dual antiplatelet therapy.
4 Aug 2015
A 49-year-old man is evaluated during a routine examination. He is asymptomatic but is concerned about his risk for cardiovascular disease. Medical history is notable for hypertension. He is a nonsmoker, and he works as an executive at a highly successful company. Family history is noncontributory. His only medication is hydrochlorothiazide. Following a physical exam and cholesterol and glucose testing, what is the most appropriate next step in management?
9 Feb 2016
Obtaining calcium from food rather than supplements is preferred, but supplements can be used safely in patients whose calcium intake is not sufficient, the report said.
25 Oct 2016
Recategorized, lower thresholds might give physicians effective new weapons in the fight against hypertension, but some contend that it's premature to change clinical practice.
1 Mar 2018
The American Heart Association (AHA) and the American College of Cardiology (ACC) released the “2014 Guideline for the Management of Patients with Non-ST-Elevation Acute Coronary Syndromes” (NSTE-ACS) last week.
30 Sep 2014
Macrolide antibiotics may be associated with a small increased risk for cardiovascular complications
While the absolute risks for sudden cardiac death and ventricular tachyarrhythmias were small, macrolides are 1 of the more commonly used antibiotic groups in many countries, and millions of patients are prescribed these drugs annually.
10 Nov 2015
This issue covers the debate about statins guidelines, evidence-based guidelines for gout, and physicians-in-training who face discrimination.
1 Apr 2017
Regular aspirin users who were switched to placebo in a randomized trial did not have increased risk of all-cause mortality or cardiovascular disease events compared with those who continued aspirin, but the findings of the post hoc analysis were inconclusive.
15 Mar 2022
The first 10 practices to sign up for the Diabetes Collaborative Registry will also have the opportunity to earn up to $2,500 for their practices.
14 Jul 2015