Search results for "Rheumatology"
Novel drug plus DMARDs may improve control of rheumatoid arthritis
Tofacitinib improved disease control in patients with active rheumatoid arthritis despite treatment with nonbiologic disease-modifying, anti-rheumatic drugs (DMARDs) compared to placebo, a study found.
https://immattersacp.org/weekly/archives/2013/08/20/5.htm
20 Aug 2013
MKSAP Quiz: follow-up visit for gout
A 55-year-old man is evaluated during a follow-up visit for gout. Two years ago, he had been treated with allopurinol and developed a hypersensitivity reaction. Over the past several months, he has had recurrent attacks of acute, episodic swelling of the first metatarsophalangeal joints with increasing involvement of other joints, including the ankles and knees. Laboratory studies showed significant hyperuricemia. History is also significant for Crohn disease, hypertension, chronic kidney disease (estimated glomerular filtration rate of 55 mL/min/1.73 m2), and nonalcoholic fatty liver disease. Current medications are diltiazem and azathioprine, which he has been taking for the past 9 months. Which of these is a contraindication to the use of febuxostat in this patient?
https://immattersacp.org/weekly/archives/2017/01/24/3.htm
24 Jan 2017
Nighttime gout attack risk may be twice as much as in daytime
The risk of acute gout attacks was more than twice as high during the night or early morning hours than the day, even among those who did not consume alcohol and had a low purine intake during the 24 hours prior to the attack, a study found.
https://immattersacp.org/weekly/archives/2014/12/16/5.htm
16 Dec 2014
NSAID use may be associated with increased VTE risk
There may be a statistically significant increased risk of venous thromboembolism (VTE) among users of nonsteroidal anti-inflammatory drugs (NSAIDs), a meta-analysis found.
https://immattersacp.org/weekly/archives/2014/09/30/4.htm
30 Sep 2014
Free educational tools available for diagnosis, treatment of lupus
Free educational resources are available through the American College of Rheumatology's Lupus Initiative to reduce health disparities for patients disproportionately affected by lupus based on race, ethnicity and gender.
https://immattersacp.org/weekly/archives/2012/09/18/9.htm
18 Sep 2012
MKSAP Quiz: 1-year history of morning stiffness, aching hands
A 23-year-old woman is evaluated for a 1-year history of morning stiffness and achiness of the hands as well as Raynaud phenomenon. Two months ago, she experienced a sun-induced rash on the chest and back and patches of discoloration on the hands. Following a physical exam and lab studies, what is the most appropriate initial treatment?
https://immattersacp.org/weekly/archives/2015/02/10/3.htm
10 Feb 2015
MKSAP Quiz: gradually progressive knee pain
A 52-year-old man is evaluated for a 5-year history of gradually progressive left knee pain. He has 20 minutes of morning stiffness, which returns after prolonged inactivity. He has minimal to no pain at rest. He reports no clicking or locking of the knee. Over the past several months, the pain has limited his ambulation to no more than a few blocks. Following a physical exam and radiograph, what is the most appropriate next diagnostic step?
https://immattersacp.org/weekly/archives/2013/04/23/3.htm
23 Apr 2013
Lupus presentation may be an ‘imitator’
Lupus can involve multiple organ systems and shares the same, sometimes nonspecific presentation as other conditions. But a diligent internist##mdash;an “excellent generalist” in the words of one expert##mdash;can pick up on the correct diagnosis.
https://immattersacp.org/archives/2014/11/lupus.htm
1 Nov 2014
4 steps to managing osteoarthritis pain in the elderly
Weight loss and nutritional counseling should be the first step, while opioids are always and only a last resort.
https://immattersacp.org/archives/2016/07/osteoarthritis.htm
1 Jul 2016
MKSAP Quiz: evaluation for progressive left knee pain
A 34-year-old man is evaluated for progressive left knee pain. The pain causes difficulty with his work as a mail carrier, particularly when walking. His occupation does not require repetitive bending. He played football in college and experienced left knee trauma during sports participation; he underwent left meniscectomy and stopped playing sports. His mother has osteoarthritis of the hands that developed at age 65 years. Following a physical exam and radiographs, what is the most likely cause of this patient's left knee osteoarthritis?
https://immattersacp.org/weekly/archives/2016/10/04/3.htm
4 Oct 2016