Current Issue

Restricting PPI prescription refills reduced use without noticeable clinical effects

Restrictions on proton-pump inhibitor (PPI) refills for patients without a documented long-term indication were associated with a rapid and sustained 7.3% absolute reduction in such prescriptions—a relative decline of nearly 30%, a Veterans Affairs study found.

Higher MAP linked with AKI reversal among hospitalized patients

A 5 mm Hg increase in mean arterial pressure (MAP) was linked with a small but significant increase in the likelihood of reversal of acute kidney injury (AKI), according to a retrospective study of patients hospitalized with decompensated cirrhosis.

GLP-1 receptor agonists could modestly delay gastric emptying during periprocedural fasting, study suggests

A systematic review and meta-analysis found that glucagon-like peptide-1 (GLP-1) receptor agonists were associated with a delay of approximately 36 minutes in gastric emptying on scintigraphy compared to placebo.

MKSAP Quiz: Follow-up of fundic gland polyps

A 55-year-old man is evaluated for follow-up of fundic gland polyps. After endoscopy and biopsy showing no dysplasia, when should a follow-up upper endoscopy be performed?

In the Clinic, 2023 summary highlight gastroenterology topics

Colorectal cancer screening was the focus of the latest In the Clinic article, while an article in a supplement to Annals reviewed clinically important developments in gastroenterology and hepatology in 2023.

Case reports cover peritonitis, rare schwannoma

Peritonitis caused by Mycoplasma hominis and pancreatic schwannoma were described in recent cases.